Fluoroquinolones: Another Warning About Nerve Damage

Today's post from stonehearthnewsletters.com (see link below) is another forceful article about the dangers of Fluoroquinolone, antimicrobial antibiotics (Levaquin, Cipro,Avelox etc) to nerve damage patients or even those who don't as yet suffer nerve damage. The evidence is now pretty much overwhelming that these antibiotics should be avoided or at least properly discussed with your doctor. Even the FDA has forced manufacturers to clearly state the dangers on their packaging. They can cause mitochondrial toxicity (simply put, they can attack the mitichondria, the energy powerhouses of nerve cells and essential for good working order) and if you already have neuropathy, make it considerably worse and if not, actually cause it. They are so widely prescribed that they're practically medical M&Ms but please talk over any prescription with your doctor or specialist, before taking them - there are alternatives available.
 

Levaquin, Cipro, Avelox May Result In Neurodegenerative Diseases 
Posted on September 2, 2014 by Stone Hearth News

HAMILTON, N.J., Sept. 2, 2014 /PRNewswire-iReach/ – Four years ago, Lisa was a physically active and healthy 45 year old. She would frequently unwind at the local gym after spending a long day on her feet teaching a class of energetic elementary school students. All of that changed dramatically when she took an antibiotic for a sinus infection. Lisa’s doctor prescribed the popular antibiotic, Levaquin, a drug she was told was safe. She became so disabled, she was unable to continue working. Lisa’s doctor was at a loss to explain the sudden onset of these painful, debilitating symptoms, particularly when they continued to worsen months after she had stopped taking the antibiotic.

Levaquin belongs to a class of antibiotics called Fluoroquinolones. Originally manufactured to treat serious, life-threatening infections, they have been increasingly used for minor infections and, in some cases, when no infection exists. A common misconception is that they are safe, despite several Black Box warnings, which include Central Nervous System (CNS) dysfunction and increased risk of tendon rupture. In August 2013, the FDA strengthened Levaquin’s warning to include the risk of Peripheral Neuropathy, which can be permanent.

While doctors have struggled to explain Fluoroquinolone Toxicity Syndrome, part of the explanation may be found in an April 17, 2013 FDA report which indicates Levaquin, Cipro, and Avelox may cause Mitochondrial Toxicity. This report, obtained through a Freedom of Information request, states that Mitochondrial Toxicity is implicated in serious, life-threatening neurodegenerative conditions, such as Parkinson’s, Alzheimer’s, and ALS.

Based on this 2013 FDA report, signed by an FDA Acting Division Director, Dr. Charles Bennett from the University of South Carolina, submitted a Citizen Petition to the FDA requesting a Black Box warning be added to the Levaquin label which would warn doctors and patients of the risk for Mitochondrial Toxicity.

Quinolone Vigilance Foundation (QVF), www.SaferPills.org, a non-profit, charitable organization that fosters, initiates, and funds research on Fluoroquinolone Toxicity, supports the Citizen Petition. Rachel Brummert, QVF Executive Director, herself injured by Levaquin in 2006, was diagnosed four years later with Neurosarcoidosis, a degenerative neurological disorder that is linked to Mitochondrial Toxicity. “The failure by the FDA and drug makers to adequately warn the public puts patients at an alarmingly high risk of developing life-threatening neurodegenerative disorders,” said Brummert. “We call on the FDA and drug makers to protect the American public and issue this important warning immediately.”

John Fratti, also damaged by Levaquin and is a staunch advocate for additional Black Box warnings, agrees with Brummert. “Doctors and patients should not have to obtain drug safety information through a Freedom of Information Act request. The boxed warning requested by the Citizen Petition is needed immediately.”

For Lisa, who still struggles with the aftermath of the damage caused by Levaquin, the requested Citizen Petition Black Box warning will come too late. It may, however, prevent others from suffering a similar fate.

Media Contact: Rachel Brummert, Quinolone Vigilance Foundation, 609-575-9839, rachel@saferpills.org

News distributed by PR Newswire iReach: https://ireach.prnewswire.com

SOURCE Quinolone Vigilance Foundation

http://www.stonehearthnewsletters.com/levaquin-cipro-avelox-may-result-neurodegenerative-diseases/neuropathy/