The Future of Research in Neuropathy ONLINE FIRST
Takayuki Itoh, MD, PhD1; David Pleasure, MD1,2 JAMA Neurol. Published online November 03, 2014
This viewpoint focuses on the technological advances in nucleotide sequencing and genetic engineering and on our deepening understanding of the molecular processes underlying Schwann cell–axon interactions and axonal degeneration.
The future isn’t what it used to be. How will the technological advances in the analysis and modulation of gene expression, in combination with a deepening understanding of the biology of the peripheral nervous system, alter the diagnosis and management of patients with peripheral neuropathies? This review focuses on the technological advances in nucleotide sequencing and genetic engineering and on our deepening understanding of the molecular processes underlying Schwann cell–axon interactions and axonal degeneration.
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