Today's post from nlm.nih.gov (see link below) the site of Medline Plus, gives an overview of a form of neuropathy that is troubling more and more people; either because it is becoming more common, or because it is being better diagnosed. It's the nightmare for all living with nerve damage, when the functions you take for granted also begin to go awry and the psychological ramifications are often underestimated, both by patient and doctor. Basically autonomic neuropathy is a collective term for the symptoms caused when the involuntary functions of the body you take for granted your whole lives, start letting you down. Reading this article will give you a good idea of what I mean. It's very important that if you notice this sort of thing happening, you contact your doctor and possibly get referred to a neurologist because each symptom/problem may need to be dealt with apart from the others. Unfortunately, at the moment, there's little that can be done to address the neuropathy itself but the symptoms may be relieved by medications and adapting your lifestyle and daily habits.
Autonomic neuropathy
Medline Plus (last updated Jan 2015)
Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage every day body functions such as blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion.
Causes
Autonomic neuropathy is a group of symptoms, not a specific disease. There are many causes.
Autonomic neuropathy involves damage to the nerves that carry information from the brain and spinal cord to the heart, bladder, intestines, sweat glands, pupils, and blood vessels.
Autonomic neuropathy may be seen with:
Alcohol abuse
Diabetes (diabetic neuropathy)
Disorders involving scarring of tissues around the nerves
Guillain Barre syndrome or other diseases that inflame nerves
HIV and AIDS
Inherited nerve disorders
Multiple sclerosis
Parkinson's disease
Spinal cord injury
Surgery or injury involving the nerves
Symptoms
Symptoms vary depending on the nerves affected. They usually develop gradually over years. Symptoms may include:
Stomach and intestines
Constipation (hard stools)
Diarrhea (loose stools)
Feeling full after only a few bites (early satiety)
Nausea after eating
Problems controlling bowel movements
Swallowing problems
Swollen abdomen
Vomiting of undigested food
Heart and lungs
Abnormal heart rate or rhythm
Blood pressure changes with position and causes dizziness when standing
High blood pressure
Shortness of breath with activity or exercise
Bladder
Difficulty beginning to urinate
Feeling of incomplete bladder emptying
Leaking urine
Other
Sweating too much or not enough
Heat intolerance brought on with activity and exercise
Sexual problems including erection problems in men and vaginal dryness and orgasm difficulties in women
Small pupil in one eye
Weight loss without trying
Exams and Tests
Signs of autonomic nerve damage are not always seen when yourdoctor or nurse examines you. Your blood pressure or heart rate may change when lying down, sitting, and standing.
Special tests to measure sweating and heart rate may be done. This is called "autonomic testing."
Other tests depend on what type of symptoms you have.
Treatment
Treatment to reverse nerve damage is most often not possible. As a result, treatment and self-care are focused on managing your symptoms and preventing further problems.
Your doctor or nurse may recommend:
Extra salt in the diet or taking salt tablets to increase fluid volume in blood vessels
Fludrocortisone or similar medications to help your body retain salt and fluid
Medicines to treat irregular heart rhythms
Pacemaker
Sleeping with the head raised
Wearing elastic stockings
The following may help your intestines and stomach work better:
Daily bowel care program
Medications that increase gastric motility (such as Reglan)
Sleeping with the head raised
Small, frequent meals
Medicines and self-care programs can help you if you have:
Urinary incontinence
Neurogenic bladder
Erection problems
Outlook (Prognosis)
How well you do depends on the cause of the problem and if it can be treated.
Possible Complications
Fluid or electrolyte imbalance such as low blood potassium (if excessive vomiting or diarrhea)
Injuries from falls (with postural dizziness)
Kidney failure (from urine backup)
Malnutrition
Psychological/social effects of impotence
When to Contact a Medical Professional
Call for an appointment with your health care provider if you have symptoms of autonomic neuropathy. Early symptoms might include:
Becoming faint or lightheaded when standing
Changes in bowel, bladder, or sexual function
Unexplained nausea and vomiting when eating
Early diagnosis and treatment increases the likelihood of controlling symptoms.
Autonomic neuropathy may hide the warning signs of a heart attack. They are sudden fatigue, sweating, shortness of breath, nausea, and vomiting.
Prevention
Preventing or controlling disorders associated with autonomic neuropathy may reduce the risk. For example, people with diabetes should closely control blood sugar levels.
Alternative Names
Neuropathy - autonomic; Autonomic nerve disease
References
Shy ME. Peripheral neuropathies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 446.
Benarroch E, Freeman R, Kaufman H. Autonomic nervous system. In: Goetz CG, eds. Textbook of Clinical Neurology. 3rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 21.
Chelimsky T, Robertson D, Chelimsky G. Disorders of the Autonomic Nervous System. In: Daroff: Bradley's Neurology in Clinical Practice. 6th ed. Philadelphia,Pa; Elsevier; 2012: chap 77.
Update Date: 10/3/2012
Updated by: Luc Jasmin, MD, PhD, Department of Neurosurgery at Cedars-Sinai Medical Center, Los Angeles, and Department of Anatomy at UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
http://www.nlm.nih.gov/medlineplus/ency/article/000776.htm
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