Saturday 17 June 2017

Claims For Seal Oil And Nerve Regeneration

Today's post from thediabeticnews.com (see link below) is the type of article that can infuriate neuropathy sufferers because it offers up hope (from the title alone) for nerve pain relief that is not based on very much at all. While certainly not 'fake news' it does come under the banner of 'non news' in that it reports something that is still in the early study phase and will take years to develop into something that can be proved to work. There's nothing wrong with the claims regarding seal oil but when the report is filled with words like 'suggests', 'could' and 'has the potential to', you know you're not reading concrete facts, so I suggest you hold back a while before searching the internet for seal oil products. I'm not suggesting that interesting theories shouldn't be published but they really should try to hold back on the lurid headlines.

Seal Oil Promotes Nerve Regeneration, Helps Diabetic Neuropathy, Says Study June 14, 2017 

 Recent study suggests that seal oil, taken as a supplement, could help with diabetic neuropathy, a form of nerve damage caused by diabetes.

A research team at the Krembil Neuroscience Centre in Toronto has published a paper that suggests seal oil has the potential to help promote nerve regeneration in patients with Type 1 diabetes.

The study found that patients who ingested an omega-3 supplement derived from seal oil twice a day over a 12-month period reported an increase in corneal nerve fibre length.

The paper entitled The effects of omega-3 supplementation on neuropathy in type 1 diabetes was published in the June, 2017 issue of Neurology, the medical journal of the American Academy of Neurology.

“Nothing like this has been attempted in humans before,” says Dr. Evan Lewis, a neurologist and one of the study’s authors. “Results from this trial are a very important step towards a clinical therapy for people with diabetic neuropathy.”

Diabetic neuropathy is a form of nerve damage caused by diabetes. Symptoms vary from patient to patient, but can include tingling, numbness, loss of sensation, a feeling of burning in the hands and feet, constant pain and difficulty walking. There are currently no therapies available for patients that stop or reverse its effects.

“This study is the first to show that targeted nutritional invention can stop and reverse small fibre damage,” says Dr. Vera Bril, head of the division of Neurology in the Department of Medicine, and Medical Director of the Ellen Prosserman Centre for Neuromuscular Diseases at UHN, and the study’s principal investigator. Other members of the research team included Dr. Bruce Perkins of the Leadership Sinai Centre for Diabetes as well as Dr. Thomas Wolever and Dr. Richard Bazinet, both of the University of Toronto’s Department of Nutritional Sciences.

The study involved 40 patients and focused primarily on corneal nerve fibre length. Located at the front of the eye, the cornea has the highest density of nerves in the body. Damage to these nerves, or loss of corneal nerve fibre length, is considered a biomarker for the progression of Type 1 diabetes. The study did not measure vision recovery.

Researchers investigated the effects of the omega-3 seal oil supplement on nerve structure and found that patients on average experienced a 29 per cent increase in corneal nerve fibre length, which is considered to be representative of small nerve fibre regeneration in other parts of the body.

“These findings suggest that use of this supplement may have the potential to have a regenerative effect,” says Dr Lewis. “Our goal was to collect enough data to power a randomized clinical trial and we believe this study lays the groundwork for that to happen.”

The next step for the research team will be to conduct a phase three randomized controlled trial involving a larger group of participants.

Funding for this study was provided by Diabetes Canada and the Banting and Best Diabetes Centre.

“The initial results of this research are very promising and Diabetes Canada looks forward to continued study on the impact of omega-3s on nerve regeneration,” said Dr. Jan Hux, Chief Science Officer at Diabetes Canada.

Source: University Health Network
Journal: Neurology
Funder: Diabetes Canada, Banting and Best Diabetes Centre

http://thediabeticnews.com/seal-oil-promotes-nerve-regeneration-helps-diabetic-neuropathy-says-study/

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