Wednesday, 4 April 2018

Gabapentin (Neurontin) Added To The List Of Public Health Danger Drugs. Where Next?

Today's alarming post from (see link below) is worrying for two reasons:- first, Gabapentin is displaying dangerous side effects for a so-called non-addictive drug and secondly, it's being added to the list of drugs contributing to the so-called pain-killer crisis. Both of these are bad news for the many neuropathy patients who have been put on to this anti-seizure drug as part of the long list of drugs to try to control nerve pain. Opioids are already famously under fire but perhaps it was only a matter of time before the media got hold of panic stories about other drugs routinely prescribed for neuropathy. You can imagine how this story is going to roll out, until anti-epilepsy and anti-depressant drugs are targeted as being dangers to public health and end up being restricted. It's an ironic coincidence that the drugs we need to lessen neuropathy symptoms, run parallel to the drugs that are being abused and criminalised - where are we going to end up? Denied the medications that make life just a little bearable...that's where. How many more patients are going to be condemned to a life of unrelenting pain before someone realises that there are genuine patients and there are drug abusers basically using the same shit? How long before the two groups can be separated in the public and media mind! It's all very depressing to say the least.

Health officials are sounding an alarm on the drug gabapentin. And it’s not even an opioid.
by Corky Siemaszko First Published Apr 1 2018

It’s fast becoming the go-to drug for addicts in search of a stronger high — and it is not even an opioid.

Gabapentin, a purportedly nonaddictive painkiller primarily used to treat shingles and control seizures, has landed on the radar of beleaguered health officials and law enforcement already battling the deadly opioid epidemic that has ripped through the Rust Belt and claimed thousands of lives across the country.
Bottles of Gabapentin drugs move through the packaging process at Teva Pharmaceutical Industries Ltd.'s headquarters on Sept. 19, 2011 in Jerusalem, Israel. Adam Reynolds / Bloomberg via Getty Images file

Kentucky last year became the first state to classify gabapentin as a controlled substance after the drug showed up in a third of the state’s fatal overdoses in 2016, as The Louisville Courier Journal first reported.

And police in Ohio have reported a dramatic rise in the abuse of gabapentin, better known by brand names like Neurontin, Gralise or Horizant. There have already been reports of 300 milligram pills being sold on the street for as little as 75 cents apiece in the college town of Athens, Ohio.

“We started hearing from pharmacists about people trying to get early refills,” Van Ingram, executive director of the Kentucky Office of Drug Control Policy, told NBC News. “That is usually a sign that something is being abused. “

So Kentucky lawmakers classified gabapentin as a Schedule 5 drug, meaning that every time it is sold it will be “reported to our prescription monitoring program,” Ingram said. “We’ll be looking at that data.”

What makes Kentucky’s move all the more unusual is that gabapentin has the seal of approval from the U.S. Centers for Disease Control and Prevention as a nonopioid treatment for chronic pain. In fact, it has been seen as a safe alternative to addictive opioid painkillers.

“I don’t want to declare war on gabapentin,” said Ingram. “I think it’s a good drug. But when it’s being used in conjunction with other drugs or alcohol there may be a problem.”

That’s because gabapentin is, in the parlance of the drug abuse experts, a “potentiate.” That means it can make already dangerous drugs like fentanyl or heroin even more lethal.

“This means that when the drugs interact in the human body, they each increase the effects caused by the other drug,” the informational website Addict Help reported. “For alcohol, this means that the alcoholic high is stronger and kicks in with less alcohol. It also means, for both drugs, that unfortunate side effects common with these drugs are equally heightened.”

So is the danger. A Canadian study published last year, which tracked patients in Ontario from August 1997 to December 2013 who had been prescribed both opioids and gabapentin for pain, found a “substantial increase in the risk of opioid-related death.”

“Clinicians should consider carefully whether to continue prescribing this combination of products and, when the combination is deemed necessary, should closely monitor their patients and adjust opioid dose accordingly,” the researchers concluded.

How did gabapentin become such the problem? The same way opioids did — through over-prescription, said Dr. James Patrick Murphy, a pain specialist based in Louisville.

“It got prescribed so much that everybody taking an opioid for chronic pain was also taking gabapentin,” said Murphy. “People have a tendency to want to abuse anything that is mind-altering and a lot of time it is what is readily available to them."

The fact is gabapentin “is not really that strong of a drug and relatively safe,” Murphy said. It is also a cousin to the nongeneric pain medications like Lyrica, sales of which have reportedly tripled in recent years.

“But some people will take a valium with opioids and some people will take a handful of gabapentin,” Murphy said. “The sad thing for patients who do well on gabapentin is that this will make physicians less likely to prescribe gabapentin.”

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